Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.67 |
| ▸ | KDR | P35968 | 10/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.67 |
| ▸ | TEK | Q02763 | 2/20 | 0.67 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.67 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | LYN | P07948 | 2/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | HCK | P08631 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | ABL2 | P42684 | 2/20 | 0.56 |
| ▸ | FRK | P42685 | 2/20 | 0.56 |
| ▸ | MST1R | Q04912 | 2/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.56 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727517 | 0.93 | MET (0.69) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL1728634 | 0.89 | MET (0.68) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL1727515 | 0.88 | MET (0.71) | METKDRNTRK1TEKNTRK3 | |
| Sulfuric Acid SCHEMBL5133938 | 0.88 | MET (0.72) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL1728382 | 0.87 | MET (0.76) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL2251542 | 0.87 | MET (0.73) | METKDRNTRK1TEKNTRK3 | |
| Bromide SCHEMBL4247685 | 0.87 | MET (0.75) | METKDRNTRK1TEKNTRK3 | |
| Hydrochloric Acid SCHEMBL1728468 | 0.87 | MET (0.75) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL12097157 | 0.86 | MET (0.65) | METKDRNTRK1TEKNTRK3 | |
| SCHEMBL2251069 | 0.86 | MET (0.65) | METKDRNTRK1TEKNTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377938-B2 | Phenoxypyridine derivative salts and crystals thereof, and process for preparing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| WO-2009142896-A3 | LANDSCAPE EDGING SYSTEM | WINK JOHN (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2062886-B1 | SALT OF PHENOXYPYRIDINE DERIVATIVE OR CRYSTAL THEREOF AND PROCESS FOR PRODUCING THE SAME | EISAI R&D MAN CO LTD (JP) | 2011-11-30 | — | — | EP | disclosed |
| EP-2062886-A1 | SALT OF PHENOXYPYRIDINE DERIVATIVE OR CRYSTAL THEREOF AND PROCESS FOR PRODUCING THE SAME | Eisai R&D Management Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
| US-20080318924-A1 | PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME | EISAI R&D MANAGEMENT CO., LTD (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318924-A1 | PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME | HGF, MET, FLT1 | MET 2/4885KDR 9/4885NTRK1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.