Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238738 | 0.87 | PTGS2 (0.52) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL9277399 | 0.85 | AKR1C3 (0.52) | AKR1C3GAAMAPTPTGDR2ABCB11 | |
| SCHEMBL2240555 | 0.85 | AKR1C3 (0.42) | AKR1C3POLBGAAMAPTL3MBTL1 | |
| SCHEMBL2235283 | 0.84 | GAA (0.46) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL10580853 | 0.83 | AKR1C3 (0.50) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL31086202 | 0.83 | AKR1C3 (0.50) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL29085116 | 0.81 | TSHR (0.50) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL30692319 | 0.77 | AKR1C3 (0.59) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL27962980 | 0.77 | AKR1C3 (0.43) | AKR1C3POLBGAAMAPTMYC | |
| SCHEMBL11445975 | 0.76 | NR4A1 (0.51) | MAPTABCB11LMNAPTGS1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890244-B2 | Thermally decomposable polymer compositions incorporating thermally activated base generators | SUMITOMO BAKELITE CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20150337081-A1 | THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS | PROMERUS, LLC (US) | 2015-11-26 | — | — | US | disclosed |