SCHEMBL31086202

SCHEMBL31086202

CCc1cccc(C(=O)c2ccccc2)c1C

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.50
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
MYC P01106 1/20 0.45
CLCN2 P51788 1/20 0.45
ALDH1A1 P00352 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP19A1 P11511 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10580853 1.00 AKR1C3 (0.50) AKR1C3POLBGAAMAPTMYC
SCHEMBL28708772 0.87 GABRA1 (0.48) GAAMAPTCLCN2ALDH1A1HPGD
SCHEMBL29085116 0.86 TSHR (0.50) AKR1C3POLBGAAMAPTMYC
SCHEMBL2238738 0.86 PTGS2 (0.52) AKR1C3POLBGAAMAPTMYC
SCHEMBL29881091 0.85 AKR1C3 (0.57) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL723171 0.85 AKR1C3 (0.57) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL9625731 0.84 AKR1C3 (0.52) AKR1C3POLBGAAMAPTMYC
SCHEMBL2235283 0.83 GAA (0.46) AKR1C3POLBGAAMAPTMYC
SCHEMBL17286641 0.83 AKR1C3 (0.44) AKR1C3POLBGAAMAPTMYC
SCHEMBL29088283 0.83 AKR1C3 (0.55) AKR1C3GAAMAPTCLCN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406781-A Screening method of raw material wheat for preparing strong-flavor Daqu 河南牧业经济学院 2024-07-30 CN disclosed