Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 17/20 | 0.54 |
| ▸ | SKP1 | P63208 | 17/20 | 0.54 |
| ▸ | SKP2 | Q13309 | 17/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727675 | 0.91 | CKS1B (0.53) | CKS1BSKP1SKP2CNR1ALDH1A1 | |
| SCHEMBL16286410 | 0.89 | CKS1B (0.47) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL1728924 | 0.88 | CNR1 (0.47) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL16286335 | 0.85 | CKS1B (0.44) | CKS1BSKP1SKP2KDM4EALDH1A1 | |
| SCHEMBL240063 | 0.84 | CKS1B (0.48) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL1729060 | 0.83 | CKS1B (0.51) | CKS1BSKP1SKP2 | |
| SCHEMBL1727911 | 0.82 | CKS1B (0.47) | CKS1BSKP1SKP2KDM4EALDH1A1 | |
| SCHEMBL16286382 | 0.82 | CKS1B (0.44) | CKS1BSKP1SKP2CNR1KDM4E | |
| SCHEMBL1729064 | 0.81 | CNR1 (0.52) | CKS1BSKP1SKP2CNR1ALDH1A1 | |
| SCHEMBL1729041 | 0.81 | NPC1 (0.55) | CKS1BSKP1SKP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |