Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | CKS1B | P61024 | 6/20 | 0.51 |
| ▸ | SKP1 | P63208 | 6/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730207 | 0.90 | CNR1 (0.50) | CNR1CKS1BSKP1SKP2SMN1; SMN2 | |
| SCHEMBL27629096 | 0.88 | CKS1B (0.53) | CNR1CKS1BSKP1SKP2USP30 | |
| SCHEMBL3266883 | 0.82 | CKS1B (0.47) | CNR1CKS1BSKP1SKP2USP30 | |
| SCHEMBL1579559 | 0.81 | HSD11B1 (0.49) | CKS1BSKP1SKP2USP30USP2 | |
| SCHEMBL3289000 | 0.81 | HTR3E (0.58) | CKS1BSKP1SKP2HSD11B1ALDH1A1 | |
| SCHEMBL1728686 | 0.81 | CKS1B (0.54) | CNR1CKS1BSKP1SKP2HPGD | |
| SCHEMBL1728924 | 0.79 | CNR1 (0.47) | CNR1CKS1BSKP1SKP2 | |
| SCHEMBL5219893 | 0.78 | DRD2 (0.56) | HSD11B1 | |
| SCHEMBL2001966 | 0.78 | ALDH1A1 (0.60) | CKS1BSKP1SKP2HPGDALDH1A1 | |
| SCHEMBL5219571 | 0.77 | HRH3 (0.55) | USP2HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |