Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 12/20 | 0.53 |
| ▸ | SKP1 | P63208 | 12/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 12/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | DKK1 | O94907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728686 | 0.91 | CKS1B (0.54) | CKS1BSKP1SKP2CNR1ALDH1A1 | |
| SCHEMBL1710740 | 0.89 | CHRM4 (0.48) | CKS1BSKP1SKP2CNR1HTR1A | |
| SCHEMBL16286410 | 0.84 | CKS1B (0.47) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL3266878 | 0.84 | CKS1B (0.45) | CKS1BSKP1SKP2CNR1HTR1A | |
| SCHEMBL1730207 | 0.83 | CNR1 (0.50) | CKS1BSKP1SKP2CNR1HTR1A | |
| SCHEMBL1710840 | 0.80 | HTR1A (0.47) | CKS1BSKP1SKP2CNR1HTR1A | |
| SCHEMBL14797005 | 0.80 | FFAR4 (0.46) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL1729030 | 0.80 | CKS1B (0.55) | CKS1BSKP1SKP2HTR1ADRD4 | |
| SCHEMBL1728924 | 0.80 | CNR1 (0.47) | CKS1BSKP1SKP2CNR1 | |
| SCHEMBL16286335 | 0.79 | CKS1B (0.44) | CKS1BSKP1SKP2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |