Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31747999 | 0.93 | KDM4E (0.47) | CNR2CNR1KDM4EGAAPDPK1 | |
| SCHEMBL22160417 | 0.93 | KDM4E (0.47) | CNR2CNR1KDM4EGAAPDPK1 | |
| SCHEMBL1940383 | 0.78 | HSP90AB1 (0.47) | CNR2CNR1KDM4EGAAPDPK1 | |
| SCHEMBL29184972 | 0.76 | KDM4E (0.45) | CNR2CNR1KDM4EGAACYP3A4 | |
| SCHEMBL28167618 | 0.71 | ALDH1A1 (0.42) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL22160420 | 0.70 | PDPK1 (0.53) | PDPK1IDO1LRRK2HTR2AHTR2C | |
| SCHEMBL22160395 | 0.70 | KDM4E (0.42) | CNR2CNR1KDM4EGAAPDPK1 | |
| SCHEMBL13502779 | 0.69 | CNR2 (1.00) | CNR2CNR1KDM4EPOLBCASP7 | |
| SCHEMBL5670563 | 0.69 | ALDH1A1 (0.43) | KDM4EGAAPOLBALDH1A1HPGD | |
| SCHEMBL10067379 | 0.67 | OPRM1 (0.48) | CNR2CNR1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092175-A1 | NOVEL P2X7 RECEPTOR ANTAGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2023-06-01 | — | — | WO | disclosed |
| US-10591497-B2 | Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family | RANDOX LABORATORIES LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
| US-10591497-B2 | Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family | RANDOX LABORATORIES LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
| EP-2950103-B1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | RANDOX LABORATORIES LTD (GB) | 2018-10-17 | — | — | EP | disclosed |
| US-20150346227-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | NORTHERN BANK LIMITED (IE) | 2015-12-03 | — | — | US | disclosed |
| US-20150346227-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | NORTHERN BANK LIMITED (IE) | 2015-12-03 | — | — | US | disclosed |
| EP-2950103-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | Randox Laboratories Ltd. (GB) | 2015-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150346227-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | CNR2, CNR1, IDO1 | CNR2 1/4885CNR1 2/4885KDM4E 2943/4885 |
| US-10591497-B2 | Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family | CNR2, CNR1, IDO1 | CNR2 1/4885CNR1 2/4885KDM4E 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.