Sugi Predict

Sugi Predict / Compounds / SCHEMBL17288010

SCHEMBL17288010

SCHEMBL17288010

Cc1nn(C)c(Nc2c(F)cc(Cl)cc2Cl)c1-c1cccc(-c2ccc(F)cc2Cl)c1F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 3/20 0.39
▸ IGF1R P08069 2/20 0.36
▸ BRD4 O60885 2/20 0.35
▸ SLC34A1 Q06495 5/20 0.35
▸ GRM4 Q14833 1/20 0.34
▸ CRHR1 P34998 2/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ SCN10A Q9Y5Y9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288009 0.92 HSD11B1 (0.39) HSD11B1IGF1RSLC34A1GRM4GRM2
SCHEMBL170613 0.91 HSD11B1 (0.39) HSD11B1IGF1RSLC34A1GRM4
SCHEMBL170838 0.86 SLC34A1 (0.42) HSD11B1SLC34A1GRM4
SCHEMBL29368805 0.86 HSD11B1 (0.40) HSD11B1IGF1RSLC34A1GRM4
SCHEMBL173677 0.86 HSD11B1 (0.40) HSD11B1IGF1RSLC34A1GRM4
SCHEMBL168744 0.85 SLC34A1 (0.41) HSD11B1IGF1RSLC34A1
SCHEMBL29369400 0.83 HSD11B1 (0.43) HSD11B1IGF1RSLC34A1
SCHEMBL170786 0.83 HSD11B1 (0.43) HSD11B1IGF1RSLC34A1
SCHEMBL17200652 0.83 HSD11B1 (0.38) HSD11B1IGF1RSLC34A1CRHR1
SCHEMBL29367611 0.83 HSD11B1 (0.42) HSD11B1IGF1RSLC34A1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2403834-B1 FUNGICIDAL PYRAZOLES DU PONT (US) 2015-12-02 — — EP claimed