SCHEMBL17288384

SCHEMBL17288384

Cc1ccc2c(c1)CC[CH]C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.36
PARP10 Q53GL7 2/20 0.35
PARP11 Q9NR21 1/20 0.35
PARP1 P09874 1/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
NOTUM Q6P988 1/20 0.33
ADRA2A P08913 1/20 0.33
ALDH1A1 P00352 4/20 0.33
ACHE P22303 1/20 0.32
AKR1C3 P42330 1/20 0.32
POLB P06746 2/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288604 0.91 METAP1 (0.36) METAP1PARP10PARP11PARP1CYP1A2
SCHEMBL3483197 0.81 METAP1 (0.41) METAP1PARP10PARP11PARP1CYP1A2
SCHEMBL17288626 0.74 DRD2 (0.46)
SCHEMBL28354723 0.74 HTR2A (0.50) METAP1PARP10PARP1ADRA2ASMN1; SMN2
SCHEMBL19926291 0.74 HTR1D (0.36) PARP10PARP1NOTUMACHERAB9A
SCHEMBL350427 0.74 DRD1 (0.51) METAP1
SCHEMBL8675519 0.72 METAP1 (0.41) METAP1PARP10PARP11PARP1CYP1A2
SCHEMBL597333 0.72 DPP4 (0.49) METAP1ADRA2AALDH1A1POLBRAB9A
SCHEMBL414198 0.72 NPC1 (0.52) METAP1ALDH1A1POLBRAB9ANPC1
SCHEMBL22005789 0.70 DPP4 (0.47) METAP1ADRA2AALDH1A1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 METAP1 3291/4885PARP10 4512/4885PARP11 4741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.