Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597333 | 0.97 | DPP4 (0.49) | DPP4NPC1RAB9APOLBRAPGEF4 | |
| SCHEMBL414198 | 0.92 | NPC1 (0.52) | DPP4NPC1RAB9APOLBRAPGEF4 | |
| Phosphonic Acid SCHEMBL11425732 | 0.85 | NPC1 (0.47) | DPP4NPC1RAB9APOLBALDH1A1 | |
| Acetic Acid SCHEMBL27990190 | 0.81 | NPC1 (0.56) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5905931 | 0.79 | CYP11B1 (0.50) | DPP4NPC1RAB9APOLBRAPGEF4 | |
| SCHEMBL17037968 | 0.79 | METAP1 (0.44) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL15957848 | 0.78 | PNMT (0.46) | ADRA2AADRA2BADRA2C | |
| SCHEMBL6905898 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10177007 | 0.76 | METAP1 (0.46) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL10232037 | 0.76 | HTR2C (0.57) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095797-B1 | ANTI DLL3 ANTIBODIES AND METHODS OF USE THEREOF | ABBVIE STEMCENTRX LLC (US) | 2020-05-20 | — | — | EP | disclosed |