SCHEMBL17288586

SCHEMBL17288586

[CH2]CCCCCC(F)(F)c1cccc2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KIF11 P52732 1/20 0.33
ACP3 P15309 2/20 0.31
ULK1 O75385 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.31
KCNJ11 Q14654 1/20 0.31
PTPRC P08575 1/20 0.31
SLC6A4 P31645 1/20 0.30
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288413 1.00 KDM4E (0.34) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL17288397 0.98 KDM4E (0.35) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL17288442 0.93 KDM4E (0.36) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL17288739 0.86 KDM4E (0.37) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL28039351 0.81 ALDH1A1 (0.33) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL28141320 0.80 HTR1B (0.38) KDM4EMEN1KMT2AALDH1A1GLA
SCHEMBL17288537 0.79 KDM4E (0.39) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL28039341 0.79 ALDH1A1 (0.34) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL28039051 0.76 HPGD (0.35) KDM4EMEN1KMT2AKIF11ACP3
SCHEMBL16933923 0.76 ABCC9 (0.38) KDM4EMEN1KMT2AACP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 KDM4E 1006/4885MEN1 2787/4885KMT2A 393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.