Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728923 | 0.89 | HRH3 (0.49) | HRH3ACACBACHEENPP1BCHE | |
| SCHEMBL1729769 | 0.88 | HRH3 (0.48) | HRH3KMT2AACACBACHEENPP1 | |
| SCHEMBL1727774 | 0.88 | HRH3 (0.48) | HRH3KMT2AACACBACHEALDH1A1 | |
| SCHEMBL1729776 | 0.87 | HRH3 (0.47) | HRH3ACACBACHEALDH1A1BCHE | |
| SCHEMBL1727924 | 0.86 | HRH3 (0.48) | HRH3ACACBMCHR1 | |
| SCHEMBL1727953 | 0.83 | PDE10A (0.45) | HRH3ALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL1730416 | 0.82 | HRH3 (0.47) | HRH3ACACB | |
| SCHEMBL1728948 | 0.82 | ENPP1 (0.43) | KMT2AACHEENPP1KDM4E | |
| SCHEMBL1729968 | 0.80 | HRH3 (0.58) | HRH3KMT2AACACBACHEENPP1 | |
| SCHEMBL3265477 | 0.78 | HRH3 (0.49) | HRH3KMT2AACACBACHEENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |