Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 10/20 | 0.44 |
| ▸ | ACACA | Q13085 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727774 | 0.92 | HRH3 (0.48) | HRH3ACACBACACAKCNH2ACHE | |
| SCHEMBL1728923 | 0.91 | HRH3 (0.49) | HRH3ACACBACACAACHEMAPT | |
| SCHEMBL1729217 | 0.87 | HRH3 (0.51) | HRH3ACACBACHEKDM4EUSP2 | |
| SCHEMBL1729769 | 0.85 | HRH3 (0.48) | HRH3ACACBACACAKCNH2ACHE | |
| SCHEMBL3266113 | 0.81 | HRH3 (0.47) | HRH3ACACBACACAKCNH2ACHE | |
| SCHEMBL1729968 | 0.80 | HRH3 (0.58) | HRH3ACACBACHEALDH1A1MAPT | |
| SCHEMBL1730141 | 0.79 | CHRM4 (0.40) | HRH3CKS1BSKP1SKP2ACHE | |
| SCHEMBL1729306 | 0.78 | HRH3 (0.46) | HRH3ACACBACACAKCNH2 | |
| SCHEMBL1728164 | 0.76 | KDM4E (0.45) | HRH3ACACBACACAKCNH2KDM4E | |
| SCHEMBL1729773 | 0.76 | HRH3 (0.44) | HRH3ACACBACACAKCNH2NAPEPLD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |