Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331013 | 0.90 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL1729060 | 0.88 | CKS1B (0.51) | CHRNA7ACHENPC1RAB9AMEN1 | |
| SCHEMBL3268959 | 0.85 | SCD (0.42) | CHRNA7ACHENPC1RAB9ABCHE | |
| SCHEMBL1728820 | 0.84 | SCD (0.49) | SCDCHRM4 | |
| SCHEMBL1728924 | 0.84 | CNR1 (0.47) | ACHECHRM4 | |
| SCHEMBL1728747 | 0.82 | SCD (0.45) | SCDCHRM4 | |
| SCHEMBL1729606 | 0.78 | CHRM4 (0.57) | CHRM4 | |
| SCHEMBL1727741 | 0.78 | CHRM4 (0.56) | CHRM4 | |
| SCHEMBL1727542 | 0.78 | HRH3 (0.52) | — | |
| SCHEMBL1727652 | 0.76 | SCD (0.42) | CHRNA7NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |