Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776419 | 0.87 | ALDH1A1 (0.52) | DRD2ALDH1A1KDM4EHSD17B10THRB | |
| SCHEMBL1729606 | 0.84 | CHRM4 (0.57) | CHRM4 | |
| SCHEMBL4417334 | 0.83 | GPR119 (0.59) | CHRM4DRD2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1728830 | 0.82 | CHRM4 (0.47) | CHRM4DRD2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1728737 | 0.82 | HSD11B1 (0.49) | CHRM4 | |
| SCHEMBL1728933 | 0.82 | KDM4E (0.54) | CHRM4ALDH1A1KDM4EGPR119THRB | |
| SCHEMBL4371640 | 0.81 | ALDH1A1 (0.54) | DRD2ALDH1A1KDM4EHSD17B10DRD3 | |
| SCHEMBL4420854 | 0.81 | DRD2 (0.51) | CHRM4DRD2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1727758 | 0.81 | CHRM4 (0.45) | CHRM4 | |
| SCHEMBL1728425 | 0.81 | HTR1A (0.51) | CHRM4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |