Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727769 | 0.90 | CHRNA7 (0.43) | SCDCHRNA7HTR3ACHRNB4CHRNA3 | |
| SCHEMBL1727572 | 0.86 | CNR1 (0.41) | — | |
| SCHEMBL1729770 | 0.85 | LMNA (0.38) | SCDMEN1KMT2A | |
| SCHEMBL1730301 | 0.85 | LMNA (0.38) | SCDMEN1KMT2A | |
| SCHEMBL1727953 | 0.81 | PDE10A (0.45) | HTR3A | |
| SCHEMBL1728042 | 0.81 | RXRA (0.46) | — | |
| SCHEMBL1728786 | 0.79 | HTR1A (0.42) | NPC1RAB9A | |
| SCHEMBL1729037 | 0.78 | HCAR2 (0.46) | HTR3ANPC1RAB9A | |
| SCHEMBL1730249 | 0.78 | HTR3A (0.42) | HTR3A | |
| SCHEMBL1730164 | 0.77 | DEGS1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |