Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705042 | 0.83 | AAK1 (0.54) | TSHRKMT2ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL4527540 | 0.78 | SMN1; SMN2 (0.43) | TSHRKMT2ASMN1; SMN2LMNAIDO1 | |
| SCHEMBL4071612 | 0.77 | SMYD3 (0.60) | SMYD3 | |
| SCHEMBL19328196 | 0.77 | AAK1 (0.39) | TSHRKDM4EL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL9373554 | 0.76 | IDO1 (0.57) | TSHRKMT2ASMN1; SMN2LMNAIDO1 | |
| Trifluoroacetic Acid SCHEMBL4527536 | 0.76 | LMNA (0.44) | TSHRKMT2ASMN1; SMN2LMNAIDO1 | |
| SCHEMBL4490876 | 0.76 | ALDH1A1 (0.51) | TSHRKMT2ASMN1; SMN2LMNAIDO1 | |
| SCHEMBL2937870 | 0.74 | TSHR (0.63) | TSHRKMT2ASMN1; SMN2LMNAIDO1 | |
| SCHEMBL38664210 | 0.74 | AAK1 (0.61) | TSHRSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL22684362 | 0.71 | PARP1 (0.46) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |