Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903601 | 1.00 | NPSR1 (0.42) | NPSR1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL5552041 | 1.00 | NPSR1 (0.42) | NPSR1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL15701448 | 0.83 | HTT (0.39) | NPSR1SMN1; SMN2ALDH1A1HTTHPGD | |
| SCHEMBL4745432 | 0.83 | CTSS (0.39) | HTTCTSSCTSK | |
| SCHEMBL13192726 | 0.83 | HTT (0.38) | SMN1; SMN2HTTHPGDTSHRCTSS | |
| SCHEMBL12631270 | 0.83 | TSHR (0.42) | SMN1; SMN2ALDH1A1HTTHPGDTSHR | |
| SCHEMBL10441262 | 0.83 | TSHR (0.42) | SMN1; SMN2ALDH1A1HTTHPGDTSHR | |
| SCHEMBL10442172 | 0.82 | ALDH1A1 (0.43) | NPSR1SMN1; SMN2ALDH1A1HTTPLA2G2A | |
| SCHEMBL191467 | 0.82 | SMN1; SMN2 (0.44) | NPSR1SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL4994 | 0.82 | SMN1; SMN2 (0.44) | NPSR1SMN1; SMN2ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440970-B1 | Benzenesulfonic acid salt of 1-(6-halogeno-2-benzothiazolyl)ethylamine | IHARA CHEMICAL IND CO (JP) | 2011-11-30 | — | — | EP | disclosed |
| WO-2011037833-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-03-31 | — | — | WO | disclosed |
| EP-1026163-B1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINES OR SALTS THEREOF | IHARA CHEMICAL IND CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-1440970-A1 | Process for producing substituted alkylamines or salts thereof | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6197969-B1 | REACTING METAL SALT OF 2-AMINOTHIOPHENOL WITH AN AMINO ACID-N-CARBOXYLIC ANHYDRIDE; CYCLIZATION IN ACID | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-1026163-A1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINES OR SALTS THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |