Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ILK | Q13418 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968511 | 0.86 | GFER (0.57) | GFERAXLUBE2TASIC3ALDH1A1 | |
| SCHEMBL30209148 | 0.86 | LOXL2 (0.65) | GFERAXLUBE2TASIC3ALDH1A1 | |
| SCHEMBL4583713 | 0.86 | LOXL2 (0.65) | GFERAXLUBE2TASIC3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5968549 | 0.85 | GFER (0.56) | GFERAXLUBE2TASIC3ALDH1A1 | |
| SCHEMBL8465212 | 0.82 | GFER (0.56) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL7222770 | 0.82 | GFER (0.56) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL6630285 | 0.82 | NPC1 (0.63) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL7547176 | 0.82 | GFER (0.56) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL3251161 | 0.80 | UBE2T (0.59) | UBE2TASIC3ALDH1A1MAPTKDM4E | |
| SCHEMBL3248623 | 0.79 | HTT (0.61) | UBE2TASIC3ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440970-B1 | Benzenesulfonic acid salt of 1-(6-halogeno-2-benzothiazolyl)ethylamine | IHARA CHEMICAL IND CO (JP) | 2011-11-30 | — | — | EP | disclosed |
| EP-1188752-B1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINE DERIVATIVE | IHARA CHEMICAL IND CO (JP) | 2006-11-29 | — | — | EP | disclosed |
| EP-1026163-B1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINES OR SALTS THEREOF | IHARA CHEMICAL IND CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-1440970-A1 | Process for producing substituted alkylamines or salts thereof | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6608207-B2 | Converting an alkali metal salt of a 2-aminothiophenol to the free base, reacting with an amino acid-N-carboxyanhydride of given formula to form a 2-(2-aminoalkyl)benzothiazole of given formula in high yield; drug, agrochemical intermediate | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030028032-A1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINE DERIVATIVE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1188752-A1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINE DERIVATIVE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |
| US-6197969-B1 | REACTING METAL SALT OF 2-AMINOTHIOPHENOL WITH AN AMINO ACID-N-CARBOXYLIC ANHYDRIDE; CYCLIZATION IN ACID | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-1026163-A1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINES OR SALTS THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028032-A1 | PROCESS FOR PRODUCING SUBSTITUTED ALKYLAMINE DERIVATIVE | NAT1, CYP4A11, CYP2B6 | GFER 878/4885AXL 2940/4885UBE2T 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.