Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 7/20 | 0.73 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.73 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.67 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.67 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.66 |
| ▸ | AHCY | P23526 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294035 | 0.99 | PRKACA (0.75) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17294015 | 0.99 | PRKACA (0.75) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17293999 | 0.98 | PRKACA (0.73) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17297714 | 0.98 | PRKACA (0.73) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17294024 | 0.96 | PRKACA (0.70) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17294000 | 0.96 | PRKACA (0.69) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL18767580 | 0.95 | PRKACA (0.70) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| SCHEMBL17294012 | 0.93 | ADORA3 (0.69) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL17293997 | 0.92 | PRKACA (0.64) | PRKACAROCK2METTL3METTL14HSP90B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL17294018 | 0.92 | PRKACA (0.64) | PRKACAROCK2METTL3METTL14HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179955-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-12-03 | — | — | WO | disclosed |