Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358069 | 0.91 | MMP14 (0.70) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL3038698 | 0.91 | MAPT (0.57) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL3038695 | 0.91 | MAPT (0.57) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL28728125 | 0.91 | MMP14 (0.70) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL9358077 | 0.91 | MMP14 (0.70) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL18660127 | 0.89 | MAPT (0.77) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL28727796 | 0.87 | MMP14 (0.65) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL16706324 | 0.84 | MAPT (0.81) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL1728626 | 0.84 | MAPT (0.70) | MAPTALDH1A1MMP14CRHBPCRHR2 | |
| SCHEMBL25223749 | 0.83 | MAPT (0.49) | MAPTALDH1A1MMP14CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566100-B | Pyrimidine compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-103193722-A | Novel quinazoline nitrogen mustard compound, and preparation method and application thereof to treatment of cancer | UNIV BEIJING NORMAL | 2013-07-10 | — | — | CN | disclosed |
| US-8476336-B2 | Ophthalmologic composition and ophthalmologic lens | ACRI.TEC GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-8476336-B2 | Ophthalmologic composition and ophthalmologic lens | ACRI.TEC GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| EP-2199834-B1 | Ophthalmological composition and ophthalmologic lens | ZEISS CARL MEDITEC AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2199834-B1 | Ophthalmological composition and ophthalmologic lens | ZEISS CARL MEDITEC AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1551810-B1 | DIARYL-SUBSTITUTED CYCLIC UREA DERIVATIVES HAVING AN MCH-MODULATORY EFFECT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-30 | — | — | EP | disclosed |
| US-20100160482-A1 | Ophthalmologic Composition And Ophthalmologic Lens | CARL ZEISS MEDITEC AG (DE) | 2010-06-24 | — | — | US | disclosed |
| US-20100160482-A1 | Ophthalmologic Composition And Ophthalmologic Lens | CARL ZEISS MEDITEC AG (DE) | 2010-06-24 | — | — | US | disclosed |
| EP-2199834-A1 | Ophthalmological composition and ophthalmologic lens | *Acri. Tec GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| EP-0733045-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| EP-0478268-B1 | Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same | NIPPON PAINT CO LTD (JP) | 1995-11-15 | — | — | EP | disclosed |
| WO-1995015952-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1995-06-15 | — | — | WO | disclosed |
| EP-0474713-B1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS | BASF AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| US-5274061-A | A 4-nitophenylaminoimido pendant group oriented by an electric field | NIPPON PAINT CO., LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| US-5204178-A | Form films of uniform thickness and maximum anisotropy, which are stable to intense laser radiation | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| US-5200552-A | POLYMERIZABLE SUBSTITUTED AMIDE COMPOUND, POLYMER OBTAINED THEREFROM AND NONLINEAR OPTICAL MATERIAL USING THE SAME | NIPPON PAINT CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0478268-A1 | Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same | Nippon Paint Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0474713-A1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS. | BASF AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015087-A1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS | BASF AKTIENGESELLSCHAFT (DE) | 1990-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160482-A1 | Ophthalmologic Composition And Ophthalmologic Lens | NR2E3, NR1H2, NR5A2 | MAPT 2745/4885ALDH1A1 2628/4885MMP14 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.