Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038695 | 1.00 | MAPT (0.57) | MAPTMMP14ALDH1A1PTGS2PTGS1 | |
| SCHEMBL1729465 | 0.91 | MAPT (0.68) | MAPTMMP14ALDH1A1CRHBPCRHR2 | |
| SCHEMBL25223749 | 0.88 | MAPT (0.49) | MAPTMMP14ALDH1A1PTGS2PTGS1 | |
| SCHEMBL8905953 | 0.88 | MAPT (0.53) | MAPTMMP14ALDH1A1PTGS2PTGS1 | |
| SCHEMBL8905957 | 0.88 | MAPT (0.53) | MAPTMMP14ALDH1A1PTGS2PTGS1 | |
| SCHEMBL25194702 | 0.87 | MAOB (0.63) | MAPTALDH1A1CRHBPCRHR2 | |
| SCHEMBL10046634 | 0.87 | MAOB (0.63) | MAPTALDH1A1CRHBPCRHR2 | |
| SCHEMBL9847342 | 0.87 | MAPT (0.68) | MAPTMMP14ALDH1A1PTGS2PTGS1 | |
| SCHEMBL8422918 | 0.85 | PTGS2 (0.51) | MAPTALDH1A1PTGS2PTGS1NPC1 | |
| SCHEMBL8645474 | 0.85 | PTGS2 (0.51) | MAPTALDH1A1PTGS2PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7537715-B2 | Self-poled electro-optic and nonlinear optical polymer, method of manufacturing the polymer, and film manufactured from the polymer | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2009-05-26 | — | — | US | claimed |
| EP-1651237-A4 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | JOHNSON & JOHNSON CONSUMER (US) | 2008-10-01 | — | — | EP | claimed |
| US-20060131548-A1 | Self-poled electro-optic and nonlinear optical polymer, method of manufacturing the polymer, and film manufactured from the polymer | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2006-06-22 | — | — | US | claimed |
| EP-1651237-A2 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | Galileo Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005016270-A2 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | claimed |
| US-20050032751-A1 | Methods for treatment of dermatological conditions | JOHNSON & JOHNSON CONSUMER INC. | 2005-02-10 | — | — | US | claimed |
| US-20100202989-A1 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | WANG BING | 2010-08-12 | — | — | US | disclosed |
| US-7737179-B2 | Methods for treatment of dermatological conditions | J&J CONSUMER COMPANIES, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-7537715-B2 | Self-poled electro-optic and nonlinear optical polymer, method of manufacturing the polymer, and film manufactured from the polymer | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2009-05-26 | — | — | US | disclosed |
| EP-1651237-A4 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | JOHNSON & JOHNSON CONSUMER (US) | 2008-10-01 | — | — | EP | disclosed |
| US-7135543-B2 | Polyamic ester having moieties of electro optic and nonlinear optical compound in side chains as an electro optic and nonlinear optical polymer, manufacturing method therefor and film manufactured therefrom | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2006-11-14 | — | — | US | disclosed |
| US-20060131548-A1 | Self-poled electro-optic and nonlinear optical polymer, method of manufacturing the polymer, and film manufactured from the polymer | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2006-06-22 | — | — | US | disclosed |
| EP-1651237-A2 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | Galileo Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| US-5007696-A | Electro-optic channel waveguide | LOCKHEED MISSILES & SPACE COMPANY, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-5006285-A | Electro-optic channel waveguide | LOCKHEED MISSILES & SPACE COMPANY, INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4957655-A | OPTICAL SWITCHES, LIGHT MODULATOR, VINYL HALIDE-ACRYLIC ESTER COPOLYMER WITH PENDANT SIDECHAIN | HOECHST CELANESE CORP. (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0378185-A2 | Copolymeric nonlinear optical media | HOECHST CELANESE CORPORATION (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4865430-A | Acrylic copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0312856-A1 | Acrylic copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4808332-A | Acrylic copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202989-A1 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | KRT18, CUTA, TUBB1 | MAPT 1044/4885MMP14 778/4885ALDH1A1 458/4885 |
| US-20050032751-A1 | Methods for treatment of dermatological conditions | KRT18, CUTA, TUBB1 | MAPT 1044/4885MMP14 778/4885ALDH1A1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.