Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.76 |
| ▸ | CA9 | Q16790 | 10/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | FNTA | P49354 | 1/20 | 0.63 |
| ▸ | FNTB | P49356 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | ACP1 | P24666 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302245 | 1.00 | FAAH (0.76) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL22386375 | 0.93 | FAAH (0.73) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17309449 | 0.93 | FAAH (0.76) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL19481515 | 0.93 | FAAH (0.76) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17302247 | 0.91 | FAAH (0.70) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17295283 | 0.91 | FAAH (0.70) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17302232 | 0.90 | CA9 (0.69) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17309395 | 0.87 | FAAH (1.00) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17295570 | 0.84 | FAAH (0.64) | FAAHCA9LMNASMN1; SMN2MEN1 | |
| SCHEMBL17295572 | 0.84 | FAAH (0.64) | FAAHCA9LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |