Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.51 |
| ▸ | ACP1 | P24666 | 6/20 | 0.51 |
| ▸ | CA9 | Q16790 | 10/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295570 | 1.00 | FAAH (0.64) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17302227 | 0.87 | PTPN1 (0.64) | PTPN1ACP1CA9CA2PTPN2 | |
| SCHEMBL17295388 | 0.84 | FAAH (0.62) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17302192 | 0.84 | FAAH (0.62) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17302245 | 0.84 | FAAH (0.76) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17295376 | 0.84 | FAAH (0.76) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17309449 | 0.81 | FAAH (0.76) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL22386375 | 0.81 | FAAH (0.73) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL19481515 | 0.81 | FAAH (0.76) | FAAHMEN1LMNAFNTAFNTB | |
| SCHEMBL17302191 | 0.81 | FAAH (0.57) | FAAHMEN1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |