Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 19/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295406 | 1.00 | S1PR1 (0.61) | S1PR1S1PR3FAAH | |
| SCHEMBL17295513 | 0.88 | MEN1 (0.61) | S1PR1S1PR3FAAH | |
| SCHEMBL17295515 | 0.88 | MEN1 (0.61) | S1PR1S1PR3FAAH | |
| SCHEMBL17295410 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3FAAH | |
| SCHEMBL17295412 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3FAAH | |
| SCHEMBL17302226 | 0.84 | FAAH (0.66) | S1PR1S1PR3FAAH | |
| SCHEMBL22420192 | 0.83 | MEN1 (0.51) | S1PR1S1PR3FAAH | |
| SCHEMBL17295493 | 0.82 | FAAH (0.45) | S1PR1S1PR3FAAH | |
| SCHEMBL17295495 | 0.82 | FAAH (0.45) | S1PR1S1PR3FAAH | |
| SCHEMBL19096258 | 0.82 | S1PR3 (0.53) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |