Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | FNTA | P49354 | 13/20 | 0.40 |
| ▸ | FNTB | P49356 | 13/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302044 | 0.85 | CYP19A1 (0.38) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL17295141 | 0.82 | FNTA (0.55) | FNTAFNTBPGGT1B | |
| SCHEMBL17295175 | 0.80 | LTB4R2 (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL17301899 | 0.75 | CYP19A1 (0.35) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL17295311 | 0.73 | NSD2 (0.37) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL17295308 | 0.73 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL17301896 | 0.72 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL17301910 | 0.71 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL17301901 | 0.71 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL17302057 | 0.70 | FNTA (0.45) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |