Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729600 | 1.00 | MAPT (0.56) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL2757301 | 0.84 | MAPT (0.47) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL27036802 | 0.81 | DRD2 (0.54) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL1729366 | 0.79 | MAPT (0.47) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL29739445 | 0.77 | MAPT (0.93) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL940256 | 0.77 | MAPT (0.93) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL22778099 | 0.76 | L3MBTL1 (0.62) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL3234060 | 0.76 | MAPT (0.70) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL27037013 | 0.75 | MAPT (0.53) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL238818 | 0.74 | MAPT (1.00) | MAPTALDH1A1LMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |