Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608638 | 0.91 | ALOX15 (0.35) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2361265 | 0.89 | HPGD (0.56) | HPGDALDH1A1KDM4ELMNAMAPT | |
| Hydrochloric Acid SCHEMBL31300224 | 0.88 | HPGD (0.54) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL18969219 | 0.87 | HTT (0.36) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL12608695 | 0.85 | CYP3A4 (0.36) | HPGDKDM4ELMNAMAPTHTT | |
| SCHEMBL12608652 | 0.82 | HPGD (0.53) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL12608636 | 0.80 | ALDH1A1 (0.35) | HPGDALDH1A1KDM4EMAPTHTT | |
| SCHEMBL12608709 | 0.78 | HPGD (0.52) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL12608683 | 0.78 | CNR2 (0.44) | HPGDALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL21441048 | 0.77 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150342927-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON, INC. | 2015-12-03 | — | — | US | disclosed |
| US-20150342927-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON, INC. | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342927-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | MALT1, PAICS, BCL9 | HPGD 212/4885ALDH1A1 633/4885KDM4E 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.