SCHEMBL17298634

SCHEMBL17298634

C=C1OC(=O)c2cc(Oc3ccc(C(C)(C)c4ccc(Oc5ccc6c(c5)C(=O)OC6=O)cc4)cc3)ccc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.39
MAOB P27338 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ADAMTS5 Q9UNA0 2/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
CYP2C9 P11712 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017616 0.97 MAOA (0.39) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL29395934 0.92 MAOA (0.45) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL74437 0.92 MAOA (0.45) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL22958490 0.91 MAOA (0.41) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL24510001 0.89 MAOA (0.43) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL22394445 0.87 MAOA (0.42) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL1501421 0.87 MAOA (0.49) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL17343179 0.87 MAOA (0.45) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL17298637 0.86 MAOA (0.39) MAOAMAOBL3MBTL1MAPTTDP1
SCHEMBL22180791 0.86 MAOB (0.41) MAOAMAOBL3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237311-A1 LOW DIELECTRIC CONSTANT, LOW DIELECTRIC DISSIPATION FACTOR COATINGS, FILMS AND ADHESIVES MIZORI FARHAD G (US) 2016-08-18 US disclosed
US-20150344627-A1 LOW MODULUS NEGATIVE TONE, AQUEOUS DEVELOPABLE PHOTORESIST DESIGNER MOLECULES, INC 2015-12-03 US disclosed