SCHEMBL24510001

SCHEMBL24510001

CC(C)(c1ccc(Oc2ccc3c(c2)C(=O)OC3=O)cc1)c1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.43
MAOB P27338 5/20 0.43
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
ALDH1A1 P00352 3/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
POLB P06746 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395934 0.97 MAOA (0.45) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL74437 0.97 MAOA (0.45) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL24949032 0.94 ESR1 (0.42) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL15695721 0.93 MAOA (0.43) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL22394445 0.93 MAOA (0.42) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL1501421 0.93 MAOA (0.49) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL22215240 0.91 MEN1 (0.43) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL22180791 0.91 MAOB (0.41) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL17282278 0.89 MAOA (0.60) MAOAMAOBTDP1MAPTL3MBTL1
SCHEMBL17298634 0.89 MAOA (0.39) MAOAMAOBTDP1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12562376-B2 Polyimide bead materials and methods of manufacture thereof ASPEN AEROGELS, INC. (US) 2026-02-24 US disclosed
US-20250223165-A1 POROUS CARBON MATERIALS COMPRISING A CARBON ADDITIVE ASPEN AEROGELS, INC. (US) 2025-07-10 US disclosed
US-20250011562-A1 AQUEOUS PROCESS FOR PREPARING POLYAMIC ACIDS AND POLYAMIC ACID RELATED GEL MATERIALS ASPEN AEROGELS, INC. (US) 2025-01-09 US disclosed
US-20240429369-A1 POLYIMIDE BEAD MATERIALS AND METHODS OF MANUFACTURE THEREOF ASPEN AEROGELS, INC. (US) 2024-12-26 US disclosed
US-20240413312-A1 CARBON POWDER CONTAINING LITHIUM IRON PHOSPHATE CATHODE MATERIALS ASPEN AEROGELS, INC. 2024-12-12 US disclosed
US-20240376273-A1 AQUEOUS POLYIMIDE PROCESSES ASPEN AEROGELS, INC. (US) 2024-11-14 US disclosed
US-12077639-B2 Aqueous polyimide processes ASPEN AEROGELS, INC. (US) 2024-09-03 US disclosed
US-20240254301-A1 WATER CO-CATALYST FOR POLYIMIDE PROCESS ASPEN AEROGELS, INC. (US) 2024-08-01 US disclosed
US-12034151-B2 Polyimide bead materials and methods of manufacture thereof ASPEN AEROGELS, INC. (US) 2024-07-09 US disclosed
US-12034151-B2 Polyimide bead materials and methods of manufacture thereof ASPEN AEROGELS, INC. (US) 2024-07-09 US disclosed
US-12034151-B2 Polyimide bead materials and methods of manufacture thereof ASPEN AEROGELS, INC. (US) 2024-07-09 US disclosed
WO-2023192443-A1 CARBON POWDER CONTAINING LITHIUM IRON PHOSPHATE CATHODE MATERIALS ASPEN AEROGELS, INC. (US) 2023-10-05 WO disclosed
US-20220185985-A1 WATER CO-CATALYST FOR POLYIMIDE PROCESSES ASPEN AEROGELS, INC. (US) 2022-06-16 US disclosed
US-20220185985-A1 WATER CO-CATALYST FOR POLYIMIDE PROCESSES ASPEN AEROGELS, INC. (US) 2022-06-16 US disclosed
US-20220185970-A1 AQUEOUS POLYIMIDE PROCESSES ASPEN AEROGELS, INC. (US) 2022-06-16 US disclosed
US-20220185970-A1 AQUEOUS POLYIMIDE PROCESSES ASPEN AEROGELS, INC. (US) 2022-06-16 US disclosed
WO-2022125839-A1 WATER CO-CATALYST FOR POLYIMIDE PROCESS ASPEN AEROGELS, INC. (US) 2022-06-16 WO disclosed
US-20220069290-A1 POLYIMIDE BEAD MATERIALS AND METHODS OF MANUFACTURE THEREOF ASPEN AEROGELS, INC. (US) 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12562376-B2 Polyimide bead materials and methods of manufacture thereof SMC3, ILK, SMC4 MAOA 3877/4885MAOB 3597/4885TDP1 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.