SCHEMBL1729932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1728879	0.83	TSHR (0.49)	TSHRHSD17B10CYP3A4KDM4ENPSR1
	SCHEMBL6294947	0.82	TSHR (0.45)	TSHRHSD17B10CYP3A4KDM4ENPSR1
	SCHEMBL3997791	0.81	TSHR (0.58)	TSHRHSD17B10CYP3A4KDM4ENPSR1
	SCHEMBL21154838	0.81	CYP4F2 (0.44)	TSHRCYP4F2CYP4A11KDM4ENPSR1
	SCHEMBL3994958	0.81	CYP4F2 (0.48)	TSHRHSD17B10CYP4F2CYP4A11CYP3A4
	SCHEMBL16530136	0.81	ALDH1A1 (0.47)	TSHRHSD17B10CYP4F2CYP4A11CYP3A4
	SCHEMBL31171420	0.81	TSHR (0.60)	TSHRHSD17B10CYP3A4KDM4ECA1
	SCHEMBL31171418	0.81	TSHR (0.60)	TSHRHSD17B10CYP3A4KDM4ECA1
	SCHEMBL16962644	0.78	TSHR (0.50)	TSHRHSD17B10CYP3A4KDM4ENPSR1
	SCHEMBL34463695	0.78	TSHR (0.50)	TSHRHSD17B10CYP4F2CYP4A11CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.