Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267876 | 0.88 | CYP4F2 (0.44) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL366265 | 0.88 | CYP4F2 (0.47) | CYP4F2CYP4A11TSHRKDM4EJMJD6 | |
| SCHEMBL30595363 | 0.84 | SOS1 (0.44) | TSHRKDM4ENPSR1CA1CA2 | |
| SCHEMBL22400318 | 0.84 | SOS1 (0.44) | TSHRKDM4ENPSR1CA1CA2 | |
| SCHEMBL6858915 | 0.84 | TSHR (0.47) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL17930513 | 0.83 | TSHR (0.46) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL16530136 | 0.82 | ALDH1A1 (0.47) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL25260946 | 0.81 | TSHR (0.47) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL1729932 | 0.81 | TSHR (0.45) | CYP4F2CYP4A11TSHRKDM4ENPSR1 | |
| SCHEMBL21154860 | 0.80 | TSHR (0.51) | CYP4F2CYP4A11TSHRKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019134680-A1 | INHIBITOR OF APOPTOSIS SIGNAL-REGULATING KINASE-1 AND APPLICATION THEREOF | 广州市恒诺康医药科技有限公司 | 2019-07-11 | — | — | WO | disclosed |