SCHEMBL17299602

SCHEMBL17299602

[2H]c1c([2H])c(-c2ccc(-c3nc(Cl)nc4ccccc34)cc2)c([2H])c([2H])c1-c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.67
ALDH1A1 P00352 6/20 0.67
LMNA P02545 4/20 0.53
MAPT P10636 4/20 0.53
ADORA2A P29274 4/20 0.49
NUDT1 P36639 3/20 0.49
HPGD P15428 2/20 0.49
GLA P06280 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 4/20 0.47
OPRK1 P41145 1/20 0.47
MEN1 O00255 3/20 0.46
ATM Q13315 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
GAA P10253 2/20 0.46
NPSR1 Q6W5P4 1/20 0.44
PKM P14618 1/20 0.43
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17299624 0.95 KDM4E (0.59) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL808191 0.92 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17286874 0.92 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17299600 0.91 KDM4E (0.73) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17299625 0.91 KDM4E (0.63) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17299631 0.91 KDM4E (0.63) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL808420 0.88 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17299607 0.85 KDM4E (0.69) KDM4EALDH1A1LMNAMAPTADORA2A
Hydrochloric Acid SCHEMBL5803147 0.84 KDM4E (0.72) KDM4EALDH1A1LMNAMAPTADORA2A
SCHEMBL17299591 0.83 KDM4E (0.54) KDM4EALDH1A1LMNAMAPTADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160020410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 US disclosed
US-20150380661-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-31 US disclosed
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380661-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 KDM4E 446/4885ALDH1A1 1383/4885LMNA 2617/4885
US-20150349276-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF ORAI2, ESR1, OR10J3 KDM4E 636/4885ALDH1A1 1715/4885LMNA 2429/4885
US-20160020410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 KDM4E 458/4885ALDH1A1 1349/4885LMNA 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.