SCHEMBL17299889

SCHEMBL17299889

c1ccc(-n2c3cc4c(cc3c3c5c(ccc32)sc2ccccc25)c2ccccc2n4-c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
HSD17B10 Q99714 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE3A Q14432 1/20 0.30
PDE11A Q9HCR9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18868357 0.89 ATM (0.47) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18868254 0.88 KDM4E (0.35) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL22011417 0.87 ATM (0.43) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18119054 0.87 CYP1A2 (0.38) KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL17300039 0.87 KDM4E (0.37) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL17299668 0.87 KDM4E (0.37) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL17299833 0.86 ATM (0.42) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL18868360 0.85 KDM4E (0.39) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL17299688 0.85 ATM (0.41) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL22186514 0.83 L3MBTL1 (0.44) KDM4EATML3MBTL1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10319918-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2019-06-11 US disclosed
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-12-07 US disclosed
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-12-07 US disclosed
US-9768394-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-19 US disclosed
US-9768394-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-19 US disclosed
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-18 US disclosed
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-18 US disclosed
WO-2015182994-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10319918-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.