Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 3/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300630 | 0.94 | KDM4E (0.36) | KDM4EPDE9AEZH2KMT2APDE1C | |
| SCHEMBL17300645 | 0.89 | KDM4E (0.38) | KDM4EPDE9AKMT2APDE1CPDE1A | |
| SCHEMBL14966529 | 0.72 | CHEK1 (0.39) | KDM4EPDE1CPDE1APDE1BALDH1A1 | |
| SCHEMBL12411024 | 0.71 | BPTF (0.36) | KDM4EPDE9APDE1CPDE1APDE1B | |
| SCHEMBL27300510 | 0.71 | PDE1C (0.39) | KDM4EPDE9APDE1CPDE1APDE1B | |
| SCHEMBL17300641 | 0.71 | KAT2B (0.37) | KDM4EPDE1CCYP1A2CYP2C19ACLY | |
| SCHEMBL18237502 | 0.70 | ALDH1A1 (0.38) | KDM4EPDE9AKMT2APDE1CPDE1A | |
| SCHEMBL10072551 | 0.69 | SMN1; SMN2 (0.51) | KDM4EPDE9AKMT2AALDH1A1CYP1A2 | |
| SCHEMBL17300634 | 0.69 | BPTF (0.37) | KDM4EPDE9AKMT2APDE1CPDE1A | |
| SCHEMBL15680578 | 0.67 | ERCC1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344502-A1 | CEPHEM COMPOUND | SHIONOGI & CO., LTD. (JP) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344502-A1 | CEPHEM COMPOUND | PRMT6, CEP170, NR0B1 | KDM4E 1616/4885PDE9A 4351/4885EZH2 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.