Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | MGLL | Q99685 | 8/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301071 | 0.89 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL21766067 | 0.89 | PTGS1 (0.36) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL17301072 | 0.85 | PTGS1 (0.33) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL23286111 | 0.84 | ALDH1A1 (0.41) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL21766064 | 0.82 | PTGS1 (0.35) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL26421391 | 0.80 | ALDH1A1 (0.38) | PTGS1PTGS2ALDH1A1BLMHPGD | |
| SCHEMBL22152333 | 0.77 | RGS4 (0.43) | — | |
| SCHEMBL17301101 | 0.75 | ALDH1A1 (0.34) | ALDH1A1BLMHPGDCYP1A2CYP2C19 | |
| SCHEMBL23296186 | 0.73 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL27561330 | 0.71 | ALDH1A1 (0.43) | PTGS1PTGS2ALDH1A1BLMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230218-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | MABPLEX INTERNATIONAL, LTD. (CN) | 2021-07-29 | — | — | US | disclosed |
| EP-3838913-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | MabPlex International Co., Ltd. (CN) | 2021-06-23 | — | — | EP | disclosed |
| WO-2021077317-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREFOR | 烟台迈百瑞国际生物医药股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-10960082-B2 | Tridentate connexon and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2021-03-30 | — | — | US | disclosed |
| EP-2949343-B1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-02-26 | — | — | EP | disclosed |
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2016-01-21 | — | — | US | disclosed |
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2016-01-21 | — | — | US | disclosed |
| EP-2949343-A1 | TRIDENTATE CONNEXON AND USE THEREOF | Newbio Therapeutics Inc. (CN) | 2015-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015832-A1 | TRIDENTATE CONNEXON AND USE THEREOF | DNTT, CD2, CD4 | PTGS1 4578/4885PTGS2 4792/4885ALDH1A1 2349/4885 |
| US-10960082-B2 | Tridentate connexon and use thereof | DNTT, CD2, CLTA | PTGS1 4587/4885PTGS2 4795/4885ALDH1A1 2383/4885 |
| US-20210230218-A1 | OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF | VIP, DNPEP, PREP | PTGS1 3480/4885PTGS2 3902/4885ALDH1A1 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.