Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451440 | 0.81 | — | — | |
| SCHEMBL9810859 | 0.76 | ALDH1A1 (0.65) | ALDH1A1 | |
| SCHEMBL9810860 | 0.76 | ALDH1A1 (0.65) | ALDH1A1 | |
| SCHEMBL6232481 | 0.76 | ALDH1A1 (0.65) | ALDH1A1 | |
| SCHEMBL9810863 | 0.76 | ALDH1A1 (0.65) | ALDH1A1 | |
| SCHEMBL1334114 | 0.76 | — | — | |
| SCHEMBL4723669 | 0.72 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL25497697 | 0.72 | — | — | |
| SCHEMBL9749165 | 0.72 | — | — | |
| SCHEMBL9749180 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | THE KITASATO INSTITUTE (JP) | 2015-12-03 | — | — | US | disclosed |
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | THE KITASATO INSTITUTE (JP) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | PDK4, PDK3, PDK2 | ALDH1A1 119/4885GSK3A 528/4885GSK3B 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.