SCHEMBL17301243

SCHEMBL17301243

O=C(Oc1ccc(OC(=O)c2ccc(-c3ccccc3)cc2)c(Cl)c1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
PDGFRB P09619 1/20 0.49
PDGFRA P16234 1/20 0.49
PARP10 Q53GL7 1/20 0.46
HPGD P15428 2/20 0.44
MCHR1 Q99705 1/20 0.44
CA9 Q16790 1/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
ALOX5 P09917 1/20 0.43
FSHR P23945 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17826638 0.88 SENP1 (0.46) MAPTKMT2ATDP1MEN1
SCHEMBL10783266 0.86 MRGPRX4 (0.49) MAPTKMT2ATDP1MEN1PARP10
SCHEMBL777889 0.83 KMT2A (0.46) MAPTKMT2ATDP1MEN1
SCHEMBL15591335 0.82 KMT2A (0.51) MAPTKMT2AMEN1
SCHEMBL17301223 0.82 MAPT (0.51) MAPTKMT2ATDP1MEN1PDGFRB
SCHEMBL27851950 0.82 MAPT (0.55) MAPTKMT2ATDP1MEN1PARP10
SCHEMBL14016864 0.82 KMT2A (0.53) MAPTKMT2AMEN1HPGD
SCHEMBL15939203 0.82 KMT2A (0.60) MAPTKMT2AMEN1
SCHEMBL17301265 0.81 KMT2A (0.59) MAPTKMT2ATDP1MEN1PDGFRB
SCHEMBL17301240 0.81 KMT2A (0.47) MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed