SCHEMBL17826638

SCHEMBL17826638

O=C(Oc1ccc(OC(=O)c2ccc(-c3ccc(O)cc3)cc2)c(Cl)c1)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.46
KMT2A Q03164 6/20 0.43
MAPT P10636 4/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 1/20 0.41
MEN1 O00255 2/20 0.41
ESR1 P03372 1/20 0.41
PKM P14618 1/20 0.41
ESR2 Q92731 1/20 0.41
HGFAC Q04756 1/20 0.41
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777889 0.95 KMT2A (0.46) SENP1KMT2AMAPTPRSS1PRSS2
SCHEMBL15591335 0.93 KMT2A (0.51) KMT2AMAPTLMNAMEN1ESR1
SCHEMBL767466 0.89 SENP1 (0.50) SENP1KMT2AMAPTKDM4ELMNA
SCHEMBL15591331 0.89 KMT2A (0.55) KMT2AMAPTLMNAMEN1ESR1
SCHEMBL17301243 0.88 MAPT (0.50) KMT2AMAPTMEN1TDP1
SCHEMBL767153 0.87 SENP1 (0.47) SENP1KMT2AMAPTPRSS1PRSS2
SCHEMBL768050 0.84 ESR1 (0.49) SENP1KMT2AMAPTMEN1ESR1
SCHEMBL777818 0.84 KMT2A (0.52) KMT2AMAPTMEN1ESR1PKM
SCHEMBL10783266 0.83 MRGPRX4 (0.49) KMT2AMAPTPRSS1PRSS2PRSS3
SCHEMBL17826637 0.82 SENP1 (0.46) SENP1KMT2AMAPTKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9366898-B2 Liquid crystal display device and method for manufacturing the same BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-06-14 US disclosed