SCHEMBL17301263

SCHEMBL17301263

C=CC(=O)OCCNC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC(=O)NCCOC(=O)C=C)cc3)c(C)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.42
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
THRB P10828 2/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 4/20 0.36
TSHR P16473 1/20 0.35
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17301277 0.85 MGLL (0.42) MGLLLMNAPOLBALDH1A1KMT2A
SCHEMBL8930016 0.85 THRB (0.41) LMNAPOLBTHRBKMT2ATSHR
SCHEMBL17301284 0.85 THRB (0.50) LMNATHRBKMT2AMAPTSMN1; SMN2
SCHEMBL18803342 0.84 NPC1 (0.44) LMNAPOLBTHRBALDH1A1KMT2A
SCHEMBL20883271 0.84 NPC1 (0.44) LMNAPOLBTHRBALDH1A1KMT2A
SCHEMBL16425803 0.84 NPC1 (0.44) LMNAPOLBTHRBALDH1A1KMT2A
SCHEMBL17301280 0.84 THRB (0.43) LMNATHRBKMT2ATSHRMAPT
SCHEMBL12794265 0.84 NPC1 (0.44) LMNAPOLBTHRBALDH1A1KMT2A
SCHEMBL12172630 0.84 THRB (0.51) LMNAPOLBTHRBKMT2AMAPT
SCHEMBL12769577 0.84 THRB (0.45) LMNAPOLBTHRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634638-B2 Liquid crystal composition, reflective layer, method for producing reflective layer, and copolymer FUJIFILM CORPORATION (JP) 2023-04-25 US disclosed
US-11332671-B2 Liquid crystal composition, method for producing reflective layer, reflective layer, cured product, and optically anisotropic body FUJIFILM CORPORATION (JP) 2022-05-17 US disclosed
US-11209688-B2 Reflective layer obtained by immobilizing cholesteric liquid crystalline phase FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
US-10942438-B2 Structure and method of manufacturing structure FUJIFILM CORPORATION (JP) 2021-03-09 US disclosed
US-20200231874-A1 LIQUID CRYSTAL COMPOSITION, REFLECTIVE LAYER, METHOD FOR PRODUCING REFLECTIVE LAYER, AND COPOLYMER FUJIFILM CORPORATION (JP) 2020-07-23 US disclosed
US-20200102500-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR PRODUCING REFLECTIVE LAYER, REFLECTIVE LAYER, CURED PRODUCT, AND OPTICALLY ANISOTROPIC BODY FUJIFILM CORPORATION (JP) 2020-04-02 US disclosed
US-20190033634-A1 METHOD FOR PRODUCING REFLECTIVE LAYER AND REFLECTIVE LAYER FUJIFILM CORPORATION (JP) 2019-01-31 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed