Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307066 | 0.88 | MAPT (0.45) | MAPTCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL17306466 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL17307079 | 0.85 | CYP19A1 (0.47) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17306718 | 0.84 | CYP19A1 (0.48) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17306755 | 0.82 | MAPT (0.47) | MAPTCYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL17306803 | 0.81 | MEN1 (0.42) | CYP11B1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL17306756 | 0.80 | PIK3CA (0.51) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17932357 | 0.80 | CYP11B1 (0.67) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31463166 | 0.80 | CYP11B1 (0.67) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19486741 | 0.80 | CYP11B1 (0.67) | CYP11B1MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |