Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306755 | 0.94 | MAPT (0.47) | MAPTKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL17306756 | 0.92 | PIK3CA (0.51) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17307079 | 0.90 | CYP19A1 (0.47) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17306718 | 0.89 | CYP19A1 (0.48) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17306463 | 0.88 | CYP11B1 (0.48) | MAPTKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL17306700 | 0.85 | MKNK1 (0.52) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL17307089 | 0.85 | MKNK1 (0.52) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL17306569 | 0.84 | HPGD (0.48) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17307061 | 0.84 | CYP1A2 (0.46) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17306624 | 0.83 | CYP19A1 (0.56) | MAPTALDH1A1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |