Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307075 | 0.94 | MAPT (0.38) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17306490 | 0.90 | DHODH (0.44) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17306492 | 0.86 | METAP1 (0.46) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL9958139 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17307083 | 0.84 | DHODH (0.42) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17932379 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17307077 | 0.84 | HSD17B10 (0.39) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL21517573 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17306797 | 0.83 | ATM (0.46) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL17306754 | 0.83 | DHODH (0.43) | ALDH1A1MAPTKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |