Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | WHR1 | P49842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306733 | 0.95 | MEN1 (0.43) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17306681 | 0.91 | ATM (0.48) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17306751 | 0.85 | ATM (0.43) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17306797 | 0.82 | ATM (0.46) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL18503977 | 0.82 | MEN1 (0.55) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL19168483 | 0.82 | MEN1 (0.50) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL24472830 | 0.81 | MEN1 (0.49) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17035071 | 0.81 | ATM (0.40) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL18504015 | 0.81 | MEN1 (0.54) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17034940 | 0.81 | DHFR (0.37) | MEN1KMT2AALDH1A1MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |