Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306686 | 1.00 | CYP1A2 (0.45) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307055 | 1.00 | CYP1A2 (0.45) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307061 | 0.99 | CYP1A2 (0.46) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17306718 | 0.94 | CYP19A1 (0.48) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307079 | 0.93 | CYP19A1 (0.47) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307021 | 0.92 | HPGD (0.49) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17306578 | 0.92 | HPGD (0.49) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307063 | 0.91 | CYP2A6 (0.49) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17306756 | 0.90 | PIK3CA (0.51) | CYP1A2CYP3A4LMNAMAPK1HIF1A | |
| SCHEMBL17307058 | 0.90 | WHR1 (0.47) | LMNAALDH1A1MEN1KMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |