SCHEMBL1730744

SCHEMBL1730744

CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCC)CC(CC)CCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPT P10636 2/20 0.57
MAPK1 P28482 2/20 0.57
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
ATM Q13315 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PRKCA P17252 1/20 0.50
PRKCE Q02156 1/20 0.50
PRKCQ Q04759 1/20 0.50
PRKCD Q05655 1/20 0.50
LPAR3 Q9UBY5 6/20 0.48
LPAR1 Q92633 3/20 0.48
ENPP2 Q13822 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LPAR2 Q9HBW0 2/20 0.47
MEN1 O00255 1/20 0.47
GMNN O75496 1/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536867 1.00 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL6536868 0.94 LMNA (0.52) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL5167478 0.88 LMNA (0.46) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL23673214 0.88 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL23673226 0.88 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL23673222 0.88 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL23673208 0.88 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL23673218 0.88 LMNA (0.58) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL30824662 0.85 MAPK1 (0.66) LMNAALDH1A1MAPTMAPK1CYP3A4
SCHEMBL1490656 0.85 MAPK1 (0.70) LMNAALDH1A1MAPTMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1671617-B1 ULTRAVIOLET PROTECTIVE PREPARATION AND COSMETICS CONTAINING THE SAME NISSHIN OILLIO GROUP LTD (JP) 2011-11-23 EP disclosed
US-7763237-B2 Ultraviolet protective preparation and cosmetics containing the same THE NISSHIN OILLIO GROUP, LTD. (JP) 2010-07-27 US disclosed
US-20070264207-A1 Ultraviolet Protective Preparation and Cosmetics Containing the Same NISSHIN OILLIO GROUP, LTD. 2007-11-15 US disclosed
EP-1671617-A1 ULTRAVIOLET PROTECTIVE PREPARATION AND COSMETICS CONTAINING THE SAME The Nisshin Oillio Group, Ltd. (JP) 2006-06-21 EP disclosed