Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GMNN | O75496 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536868 | 0.94 | LMNA (0.52) | LMNATSHRALDH1A1CYP3A4ATM | |
| SCHEMBL6536867 | 0.88 | LMNA (0.58) | LMNATSHRALDH1A1CYP3A4ATM | |
| SCHEMBL1730744 | 0.88 | LMNA (0.58) | LMNATSHRALDH1A1CYP3A4ATM | |
| SCHEMBL28366158 | 0.85 | MAPK1 (0.57) | LMNATSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL9226830 | 0.85 | MAPK1 (0.57) | LMNATSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL28883659 | 0.84 | MAPK1 (0.55) | LMNATSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL29462380 | 0.83 | LMNA (0.52) | LMNATSHRALDH1A1CYP3A4ATM | |
| SCHEMBL10098411 | 0.83 | CYP3A4 (0.51) | LMNATSHRALDH1A1CYP3A4ATM | |
| SCHEMBL1982696 | 0.82 | KDM4C (0.49) | LMNATSHRALDH1A1MAPK1MAPT | |
| 1,4-Butanediol SCHEMBL25229831 | 0.81 | MAPK1 (0.52) | LMNATSHRALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078066-A1 | Lubricant formulations containing extreme pressure agents | AFTON CHEMICAL CORPORATION | 2007-04-05 | — | — | US | disclosed |
| EP-1770155-A1 | Lubricant formulations containing extreme pressure agents with improved solubility | Afton Chemical Corporation (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1188813-B1 | Lubricants comprising friction modifiers | AFTON CHEMICAL INTANGIBLES LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| US-6444622-B1 | COMPRISING AN OIL (PREFERABLY MINERAL OIL), AN AMINOGUANIDINE OLEAMIDE AND A PHOSPHORUS AND BORON CONTAINING POLYISOBUTENYL (PIB) SUCCINIMIDE DISPERSANT; IMPROVEMENTS IN AXLE EFFICIENCY AND THE REDUCTION IN AXLE SUMP TEMPERATURES | ETHYL CORPORATION | 2002-09-03 | — | — | US | disclosed |
| US-20020055440-A1 | Friction modified lubricants | AFTON CHEMICAL INTANGIBLES LLC | 2002-05-09 | — | — | US | disclosed |
| EP-1191090-A2 | Gear oil formulations having enhanced perfomance | ETHYL CORPORATION (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1188813-A1 | Lubricants comprising friction modifiers | ETHYL CORPORATION (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6303547-B1 | ADDITIVE OF REACTION PRODUCT OF CARBOXYLIC ACID AND AMINE FROM GUANIDINE, AMINOGUANIDINE, UREA, THIOUREA AND SALTS | ETHYL CORPORATION | 2001-10-16 | — | — | US | disclosed |