Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607658 | 0.90 | PARP15 (0.54) | PARP15PARP10LMNAHTTAPP | |
| SCHEMBL12015518 | 0.79 | PARP15 (0.49) | PARP15PARP10HTTSNRNP200RAB9A | |
| SCHEMBL278312 | 0.79 | ALOX5 (0.48) | PARP15PARP10LMNAHTTTDP1 | |
| SCHEMBL325899 | 0.77 | PARP15 (0.47) | PARP15PARP10TDP1SNRNP200ACACB | |
| SCHEMBL18347810 | 0.77 | PARP15 (0.44) | PARP15PARP10LMNAHTTAPP | |
| SCHEMBL28406646 | 0.76 | PARP15 (0.46) | PARP15PARP10LMNAHTTTDP1 | |
| SCHEMBL15607657 | 0.76 | PARP15 (0.43) | PARP15PARP10LMNAHTTAPP | |
| SCHEMBL15474277 | 0.74 | PARP15 (0.47) | PARP15PARP10HTTTDP1SNRNP200 | |
| SCHEMBL18745394 | 0.71 | PARP15 (0.44) | PARP15PARP10LMNAHTTACACB | |
| SCHEMBL26071076 | 0.70 | PARP15 (0.48) | PARP15PARP10LMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447102-B2 | Protein kinase inhibitors | PHARMASCIENCE, INC. (CA) | 2016-09-20 | — | — | US | disclosed |
| US-20150344478-A1 | PROTEIN KINASE INHIBITORS | GB005, INC. | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344478-A1 | PROTEIN KINASE INHIBITORS | TEC, BTK, LCK | PARP15 1007/4885PARP10 932/4885LMNA 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.