Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 8/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26071078 | 0.81 | F2 (0.37) | F2ACACBTDP1NPC1ALDH1A1 | |
| SCHEMBL26071009 | 0.80 | NPC1 (0.39) | F2NPC1RAB9AGUSBSMPD1 | |
| SCHEMBL26071082 | 0.80 | ALOX15 (0.36) | F2LMNANPC1ALDH1A1RAB9A | |
| SCHEMBL26071074 | 0.79 | F2 (0.37) | F2NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL26071011 | 0.79 | NPC1 (0.42) | F2ACACBNPC1ALDH1A1RAB9A | |
| SCHEMBL26070954 | 0.77 | AGXT (0.43) | F2TDP1NPC1RAB9AGUSB | |
| SCHEMBL26071042 | 0.77 | SMN1; SMN2 (0.38) | F2LMNAHTTNPC1ALDH1A1 | |
| SCHEMBL26070929 | 0.76 | F2 (0.46) | F2 | |
| SCHEMBL26071073 | 0.75 | SMPD1 (0.60) | F2ALDH1A1RAB9AGUSBSMPD1 | |
| SCHEMBL26070590 | 0.75 | NR4A2 (0.56) | F2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |