Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.57 |
| ▸ | F7 | P08709 | 4/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | PPARD | Q03181 | 4/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.57 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307881 | 0.98 | ACLY (0.77) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL17307879 | 0.96 | ACLY (0.67) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL8006596 | 0.95 | ACLY (0.81) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL3617659 | 0.88 | ACLY (0.77) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL13735034 | 0.88 | ACLY (0.77) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL11863724 | 0.88 | ACLY (0.77) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL3626408 | 0.88 | ACLY (0.77) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL3209530 | 0.87 | ALDH1A1 (0.55) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL14768005 | 0.87 | ALDH1A1 (0.55) | ACLYALDH1A1PPARGCYP19A1F7 | |
| SCHEMBL3216321 | 0.87 | ALDH1A1 (0.55) | ACLYALDH1A1PPARGCYP19A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2017-11-16 | — | — | US | disclosed |
| US-20150344402-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344402-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | JIVA PHARMA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344402-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | PPARA, PPARG, PPARD | ACLY 859/4885ALDH1A1 2441/4885PPARG 2/4885 |
| US-20170327455-A1 | Omefibrates for Treating Dyslipidemia and Cardiovascular Disease | PPARA, PPARG, PPARD | ACLY 859/4885ALDH1A1 2441/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.